Early Prediction of Liver Cirrhosis Up to Two Years in Advance: A Machine Learning Study Benchmarking Against the FIB-4 and APRI Scores

arXiv:2601.00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores. Methods: We conducted a retrospective cohort study using de-identified EHR data from a large academic health system. XGBoost models were developed for 1- and 2-year prediction horizons, with model-specific feature selection and Bayesian hyperparameter tuning applied

Source: arXiv cs.LG — read the full report at the original publisher.

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