SIGNALQuantum·Jul 8, 2026, 12:00 AMSignal75Medium term

How to advance revolutionary science: high turnover, high risk and a licence to fail

How to advance revolutionary science: high turnover, high risk and a licence to fail

Nature, Published online: 08 July 2026; doi:10.1038/d41586-026-02090-7 Kathleen Fisher reveals the recipe for funding innovative science that she brings to the UK Advanced Research and Invention Agency.

Why this matters
Why now

The UK's Advanced Research and Invention Agency (ARIA) is actively seeking to define and implement its funding strategy for 'revolutionary science', making Fisher's proposed recipe timely and relevant.

Why it’s important

This outlines a blueprint for funding high-risk, high-reward scientific research, which is crucial for breakthroughs that could impact future technologies, economic competitiveness, and national security.

What changes

A shift towards institutionalizing a 'high turnover, high risk, licence to fail' approach to science funding represents a departure from traditional, more conservative research funding models.

Winners
  • · UK's scientific research sector
  • · Deep tech startups
  • · High-risk, interdisciplinary researchers
Losers
  • · Traditional, incrementally focused research institutions
  • · Bureaucratic grant approval processes
  • · Risk-averse funding bodies
Second-order effects
Direct

Increased funding and flexibility for speculative, potentially transformative scientific projects within the UK.

Second

Accelerated development of foundational technologies and scientific disciplines, potentially fostering new industries or significantly advancing existing ones.

Third

Enhanced scientific and technological sovereignty for the UK, reducing reliance on external innovation and potentially attracting global talent.

Editorial confidence: 90 / 100 · Structural impact: 60 / 100
Original report

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