
arXiv:2507.12927v2 Announce Type: replace Abstract: The general trace reconstruction problem seeks to recover an original sequence from its noisy copies independently corrupted by insertions, deletions, and substitutions. This problem arises in applications such as DNA data storage, a promising storage medium due to its high information density and longevity. However, errors introduced during DNA synthesis, storage, and sequencing require correction through algorithms and codes, with trace reconstruction often used as part of data retrieval. In this work, we propose TReconLM, a decoder-only tr
The increasing sophistication of language models provides a novel and powerful approach to complex data reconstruction challenges, intersecting with growing needs in novel data storage and retrieval systems like DNA storage.
This development indicates a convergence of advanced AI (language models) with critical data handling challenges in emerging technologies, suggesting potential breakthroughs in data integrity, storage density, and long-term archiving.
The application of decoder-only transformer models to trace reconstruction fundamentally shifts the methodology for error correction in highly noisy data streams, particularly for DNA-based storage.
- · DNA data storage companies
- · AI research and development
- · Biotechnology sector
- · Data integrity services
- · Traditional error correction methods
- · Organizations with high data loss rates
Improved reliability and capacity for DNA data storage systems due to more robust error correction.
Accelerated adoption and commercialization of DNA data storage, leading to new paradigms in archival and high-density information storage.
Reduced physical footprints for massive data centers as DNA storage becomes more viable, impacting real estate and energy demands for digital infrastructure.
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