arXiv:2605.25388v1 Announce Type: new Abstract: Nucleotide sequences constitute the fundamental genetic basis of biological systems, rendering viral genomic analysis critical for biomedical advancement. Despite progress in biological foundation models, specifically nucleotide foundation models (NFMs), the field lacks a unified standard for viral genomics to facilitate community development and enforce biosecurity constraints. To address this, we introduce ViroBench, the first comprehensive and large-scale benchmark specifically designed for NFMs in viral settings. ViroBench evaluates models ac
The proliferation of biological foundation models necessitates robust benchmarks to ensure responsible development and applications in critical areas like viral genomics.
A standardized benchmark for viral genomics using nucleotide foundation models can accelerate biomedical advancements and enhance biosecurity measures globally.
The introduction of ViroBench provides a unified evaluation framework, promoting rigorous development and comparison of AI models in understanding and combating viral threats.
- · Biomedical researchers
- · AI model developers
- · Public health organizations
- · Developers of unvalidated NFM models
- · Fragmented research efforts
Improved accuracy and reliability of AI models in analyzing viral genomics will lead to faster disease identification.
Enhanced biosecurity capabilities through better understanding and prediction of viral evolution and spread.
The acceleration of new therapeutic and vaccine developments due to advanced genomic insights.
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Read at arXiv cs.LG